65 research outputs found

    An Internet of Things (IoT) Based Approach to Innovate Canteen Stores Department’s Retail Operations

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    Excerpt from the Proceedings of the Nineteenth Annual Acquisition Research SymposiumIn the arena of globalization and competitive business environments, there is an emergent need for retail organizations to capitalize on technological tools and solutions. Retailers that adopt Internet of Things (IoT) technologies improve customer experiences and achieve cost savings. In this regard, the Pakistani-based retail chain Canteen Stores Department (CSD) can use IoT technologies to enhance its competitive advantage. This study aims to create a deeper understanding of how CSD retail operations can use IoT technologies to significantly modernize and improve CSD’s business offerings.Approved for public release; distribution is unlimited

    AN INTERNET OF THINGS–BASED APPROACH TO INNOVATE CANTEEN STORES DEPARTMENT’S RETAIL OPERATIONS

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    In a competitive business environment, retail organizations in the Western world are capitalizing on technological tools and solutions to enhance customer experience and boost sales. Specifically, retailers that adopt Internet of Things (IoT) technologies improve customer experience and achieve cost savings. Yet such innovation is rare outside the Western world. Hence, early adopters of IoT technologies in retail operations in Pakistan could gain a competitive advantage. This study aims to create a deeper understanding of how Pakistan-based Canteen Stores Department (CSD), a retail chain mainly serving service members and their families, can use IoT technologies to significantly modernize and improve its operations and distinguish itself from competitors. To do so, this study conducts a qualitative analysis of scholarly articles on the relevant technologies and on IoT-based products offered by commercial companies. The authors also include findings from discussions with CSD customers and management. The results of the study indicate CSD can use IoT technologies to optimize store layout, offer interactive in-store mapping, automate checkout systems, implement smart shelving and digital price tagging, improve in-store promotions, enhance customer relationship management, and modernize distribution, transportation, and warehousing. The study also offers CSD management guidance on how to implement IoT technologies into retail operations at one location as a pilot.Outstanding ThesisLieutenant Commander, Pakistan NavyWing Commander, Pakistan Air ForceLieutenant Colonel, Pakistan ArmyApproved for public release. Distribution is unlimited

    A low profile, dual-band, dual polarized antenna for indoor/outdoor wearable application

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    A planar, low-profile, dual-band and dual-polarized antenna on a semi-flex substrate is proposed in this paper. The antenna is fabricated on Rogers substrate with a thickness of 3.04 mm and sized at 70.4×76.14×3.11 mm3 (0.37λ0 ×0.40λ0 ×0.016λ0) only. The circular polarization property is enabled in the global navigation satellite system (GNSS) L1/E1 (lower) band by introducing a complementary split ring resonator on the antenna patch. Meanwhile, the antenna operates in the second (upper) 2.45 GHz WLAN band is enabled by etching a U-shaped slot on its ground plane. This simultaneous, dual-band and dual-polarized operation enables the proposed antenna to be applied in the indoor/outdoor wearable application. To isolate the antenna against the influence of the human body, a multiband artificial magnetic conductor (AMC) plane is added on the reverse side of the dual-band radiator. Comparison of the antenna without AMC in free space and when evaluated on the chest of a human body backed by AMC showed improved gain; from 3–5.1 dBi in the lower band, and from 1.53–5.03 dBi in the upper band. Besides that, the front-to-back ratio of the AMC backed monopole antenna also improved from 11–21.88 dB and from 2.5–24.5 dB in the GNSS and WLAN bands, respectively. Next, the specific absorption rate (SAR) of the monopole antenna with and without the AMC plane is assessed. Evaluation results indicate that the maximum SAR value decreased by up to 89.45 % in comparison with the antenna without AMC in the lower band. This indicates the effectiveness of the AMC array in increasing gain and FBR, besides reducing EM absorption in the human body

    Studies on the role of goat heart galectin-1 as an erythrocyte membrane perturbing agent

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    AbstractGalectins are β-galactoside binding lectins with a potential hemolytic role on erythrocyte membrane integrity and permeability. In the present study, goat heart galectin-1 (GHG-1) was purified and investigated for its hemolytic actions on erythrocyte membrane. When exposed to various saccharides, lactose and sucrose provided maximum protection against hemolysis, while glucose and galactose provided lesser protection against hemolysis. GHG-1 agglutinated erythrocytes were found to be significantly hemolyzed in comparison with unagglutinated erythrocytes. A concentration dependent rise in the hemolysis of trypsinized rabbit erythrocytes was observed in the presence of GHG-1. Similarly, a temperature dependent gradual increase in percent hemolysis was observed in GHG-1 agglutinated erythrocytes as compared to negligible hemolysis in unagglutinated cells. The hemolysis of GHG-1 treated erythrocytes showed a sharp rise with the increasing pH up to 7.5 which became constant till pH 9.5. The extent of erythrocyte hemolysis increased with the increase in the incubation period, with maximum hemolysis after 5h of incubation. The results of this study establish the ability of galectins as a potential hemolytic agent of erythrocyte membrane, which in turn opens an interesting avenue in the field of proteomics and glycobiology

    A Recent Approach towards Fluidic Microstrip Devices and Gas Sensors: A Review

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    This paper aims to review some of the available tunable devices with emphasis on the techniques employed, fabrications, merits, and demerits of each technique. In the era of fluidic microstrip communication devices, versatility and stability have become key features of microfluidic devices. These fluidic devices allow advanced fabrication techniques such as 3D printing, spraying, or injecting the conductive fluid on the flexible/rigid substrate. Fluidic techniques are used either in the form of loading components, switching, or as the radiating/conducting path of a microwave component such as liquid metals. The major benefits and drawbacks of each technology are also emphasized. In this review, there is a brief discussion of the most widely used microfluidic materials, their novel fabrication/patterning methods

    Wearable antennas: a review of materials, structures, and innovative features for autonomous communication and sensing

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    Wearable antennas have gained much attention in recent years due to their attractive features and possibilities in enabling lightweight, flexible, low cost, and portable wireless communication and sensing. Such antennas need to be conformal when used on different parts of the human body, thus need to be implemented using flexible materials and designed in a low profile structure. Ultimately, these antennas need to be capable of operating with minimum degradation in proximity to the human body. Such requirements render the design of wearable antennas challenging, especially when considering aspects such as their size compactness, effects of structural deformation and coupling to the body, and fabrication complexity and accuracy. Despite slight variations in severity according to applications, most of these issues exist in the context of body-worn implementation. This review aims to present different challenges and issues in designing wearable antennas, their material selection, and fabrication techniques. More importantly, recent innovative methods in back radiations reduction techniques, circular polarization (CP) generation methods, dual polarization techniques, and providing additional robustness against environmental effects are first presented. This is followed by a discussion of innovative features and their respective methods in alleviating these issues recently proposed by the scientific community researching in this field

    Validation of plasma protein glycation and oxidation biomarkers for the diagnosis of autism

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    Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder in children. It is currently diagnosed by behaviour-based assessments made by observation and interview. In 2018 we reported a discovery study of a blood biomarker diagnostic test for ASD based on a combination of four plasma protein glycation and oxidation adducts. The test had 88% accuracy in children 5–12 years old. Herein, we present an international multicenter clinical validation study (N = 478) with application of similar biomarkers to a wider age range of 1.5–12 years old children. Three hundred and eleven children with ASD (247 male, 64 female; age 5.2 ± 3.0 years) and 167 children with typical development (94 male, 73 female; 4.9 ± 2.4 years) were recruited for this study at Sidra Medicine and Hamad Medical Corporation hospitals, Qatar, and Hospital Regional Universitario de Málaga, Spain. For subjects 5–12 years old, the diagnostic algorithm with features, advanced glycation endproducts (AGEs)—Nε-carboxymethyl-lysine (CML), Nω-carboxymethylarginine (CMA) and 3-deoxyglucosone-derived hydroimidazolone (3DG-H), and oxidative damage marker, o,o’-dityrosine (DT), age and gender had accuracy 83% (CI 79 – 89%), sensitivity 94% (CI 90–98%), specificity 67% (CI 57–76%) and area-under-the-curve of receiver operating characteristic plot (AUROC) 0.87 (CI 0.84–0.90). Inclusion of additional plasma protein glycation and oxidation adducts increased the specificity to 74%. An algorithm with 12 plasma protein glycation and oxidation adduct features was optimum for children of 1.5–12 years old: accuracy 74% (CI 70–79%), sensitivity 75% (CI 63–87%), specificity 74% (CI 58–90%) and AUROC 0.79 (CI 0.74–0.84). We conclude that ASD diagnosis may be supported using an algorithm with features of plasma protein CML, CMA, 3DG-H and DT in 5–12 years-old children, and an algorithm with additional features applicable for ASD screening in younger children. ASD severity, as assessed by ADOS-2 score, correlated positively with plasma protein glycation adducts derived from methylglyoxal, hydroimidazolone MG-H1 and Nε(1-carboxyethyl)lysine (CEL). The successful validation herein may indicate that the algorithm modifiable features are mechanistic risk markers linking ASD to increased lipid peroxidation, neuronal plasticity and proteotoxic stress.</p

    A low profile, dual-band, dual polarized antenna for indoor/outdoor wearable application

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    A planar, low-profile, dual-band and dual-polarized antenna on a semi-flex substrate is proposed in this paper. The antenna is fabricated on Rogers substrate with a thickness of 3.04 mm and sized at 70.4 × 76.14 × 3.11 mm3 ( 0.37λ0 × 0.40λ 0× 0.016 λ 0 ) only. The circular polarization property is enabled in the global navigation satellite system (GNSS) L1/E1 (lower) band by introducing a complementary split ring resonator on the antenna patch. Meanwhile, the antenna operates in the second (upper) 2.45 GHz WLAN band is enabled by etching a U-shaped slot on its ground plane. This simultaneous, dual-band and dual-polarized operation enables the proposed antenna to be applied in the indoor/outdoor wearable application. To isolate the antenna against the influence of the human body, a multiband artificial magnetic conductor (AMC) plane is added on the reverse side of the dual-band radiator. Comparison of the antenna without AMC in free space and when evaluated on the chest of a human body backed by AMC showed improved gain; from 3-5.1 dBi in the lower band, and from 1.53-5.03 dBi in the upper band. Besides that, the front-to-back ratio of the AMC backed monopole antenna also improved from 11-21.88 dB and from 2.5-24.5 dB in the GNSS and WLAN bands, respectively. Next, the specific absorption rate (SAR) of the monopole antenna with and without the AMC plane is assessed. Evaluation results indicate that the maximum SAR value decreased by up to 89.45% in comparison with the antenna without AMC in the lower band. This indicates the effectiveness of the AMC array in increasing gain and FBR, besides reducing EM absorption in the human body

    Evolutionary Integrated Heuristic with Gudermannian Neural Networks for Second Kind of Lane–Emden Nonlinear Singular Models

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    In this work, a new heuristic computing design is presented with an artificial intelligence approach to exploit the models with feed-forward (FF) Gudermannian neural networks (GNN) accomplished with global search capability of genetic algorithms (GA) combined with local convergence aptitude of active-set method (ASM), i.e., FF-GNN-GAASM to solve the second kind of Lane–Emden nonlinear singular models (LE-NSM). The proposed method based on the computing intelligent Gudermannian kernel is incorporated with the hidden layer configuration of FF-GNN models of differential operatives of the LE-NSM, which are arbitrarily associated with presenting an error-based objective function that is used to optimize by the hybrid heuristics of GAASM. Three LE-NSM-based examples are numerically solved to authenticate the effectiveness, accurateness, and efficiency of the suggested FF-GNN-GAASM. The reliability of the scheme via statistical valuations is verified in order to authenticate the stability, accuracy, and convergence

    Modification of the drug resistance of emerging milk-borne pathogens through sodium alginate-based antibiotics and nanoparticles

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    Streptococcus agalactiae and Klebsiella pneumoniae are emerging as major milk-borne pathogens. Additionally, resistance to antibiotics of pathogens is of concern. Therefore, this study investigated the prevalence and drug resistance of S. agalactiae and K. pneumoniae in mastitis milk samples and assessed the antimicrobial potential of sodium alginate (G)-stabilized MgO nanoparticles (M) and antibiotics (tylosin [T] and ampicillin [A]) against both of these pathogens. A total of n = 200 milk samples from cattle were collected using purposive sampling, and standard microbiological approaches were adopted to isolate target bacteria. Parametric and non-parametric statistical tests were used to analyze the obtained data. Four preparations, GT (gel-stabilized tylosin), GA (gel-stabilized ampicillin), GTM (tylosin and MgO nanoparticles stabilized in gel), and GAM (ampicillin and MgO nanoparticles stabilized in gel), were evaluated against both bacteria through well diffusion and broth microdilution method. The analysis revealed that 45.24% (95/210) of the milk samples were positive for mastitis, of which 11.58% (11/95) were positive for S. agalactiae and 9.47% (9/95) were positive for K. pneumoniae. S. agalactiae had a significantly higher zone of inhibition (ZOI) than K. pneumoniae against penicillin, tetracycline, and amoxicillin, whereas the opposite was observed against imipenem and erythromycin. All gel (G)-based preparations showed an increase in the percentage of ZOI compared with antibiotics alone, with GTM presenting the highest of all, i.e., 59.09 and 56.25% ZOI compared with tylosin alone against S. agalactiae and K. pneumoniae, respectively. Similarly, in a broth microdilution assay, the lowest MIC was found for K. pneumoniae (9.766 ± 0.0 μg/mL) against GTM, followed by GT, GAM, and GA after incubation for 24 h. A similar response was noted for preparations against S. agalactiae but with a comparatively higher MIC. A significant reduction in MIC with respect to incubation time was found at 8 h and remained until at 20 h against both pathogens. The cytotoxicity of the MgO nanoparticles used in this study was significantly lower than that of the positive control. Overall, this study found that K. pneumoniae and S. agalactiae appeared higher in prevalence and antimicrobial resistance, and sodium alginate-based antibiotics and MgO nanoparticles were effective alternative approaches for tackling antimicrobial resistance
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